home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
The PC-SIG Library 10
/
The PC-Sig Library - Shareware for the IBM PC and Compatibles (PC-SIG)(Tenth Edition Disks 1-2804)(1991).iso
/
PC_SIGCD
/
20
/
5
/
DISK2051.ZIP
/
TAP.EXE
/
MEMORIAL.HB!
< prev
next >
Wrap
Text File
|
1990-09-29
|
7KB
|
135 lines
==================================================================
Dedication
==================================================================
It started as a way to spend a rainy Saturday afternoon, and it
ended up profoundly affecting the lives of tens of thousands of
people.
Howard Benner through TAPCIS brought to life for many of us the
very idea of an online community. His legacy is a part of our work
and our play every single day.
=================================================================
Howard Benner died in June of 1990 at the age of 44 due to
complications of malignant melanoma. Howard's pioneering work has
made access to CompuServe easy for us. Unfortunately, much
pioneering work in melanoma treatment remains to be performed.
Malignant melanoma is a highly malignant cancer of the skin. It
is the ninth most common cancer in the US and is now the most
common cancer in women between ages 25 and 29. The incidence of
melanoma has doubled in the past 10 years. In 1989, over 27,000
new cases of melanoma were diagnosed, and there were 6,000 deaths
from the disease.
There is a strong causal relationship between excessive exposure
to sun and melanoma. Many investigators believe that the rise in
the rate of melanoma is closely related to the desire for a
perpetual sun tan. Depletion of the ozone layer and the
consequent reduction in ultra-violet filtration has also been
implicated in the rising rate of melanoma occurrence. Support for
the conclusion that excessive tanning is causal in the development
of melanoma is the site of onset, in men on the back, shoulders,
or abdomen and in women on the legs, all sites that are only
occasionally subject to sunlight and thus easily "sun-burned".
According to the American Cancer Society, people who have had 3 or
more blistering sunburns are at 5 times the risk for developing
melanoma compared to people who have never been burned. There are
many today who feel that even gradual tanning is not safe.
Of considerable concern is the feeling that melanoma may remain
dormant for many years. Thus melanomas initiated 20-30 years ago
before strong sun-screens were available may first be coming
apparent now.
Risk factors also include fair complexion, family history, and a
markedly freckled back or shoulders. The incidence of melanoma
amongst Caucasians is significantly greater than that in Blacks or
Orientals.
In its initial stages, melanoma is treatable and curable. There
is a definite cutoff point between the size and thickness of the
melanoma lesion and its curability. In its early stage, melanoma
is treated by surgical excision with almost 100% cure. However,
beyond a very sharply defined lesion size (thickness > 0.75mm),
melanoma becomes essentially 100% fatal today.
Today, metastatic (spread) melanoma remains incurable. However, in
the past few years several new approaches to therapy have shown
considerable promise. New approaches include developing a vaccine
which kills melanoma cells. An experimental melanoma vaccine has
been derived by infecting melanoma cells grown in cell culture
with a virus and then injecting material from these cells into
melanoma patients to induce the production of antibodies to the
viral/melanoma combination. In initial trials of this "vaccine",
there has been a significant decrease in disease recurrence in
patients with metastatic melanoma. It is possible that high-risk
patients may some day be able to receive an anti-melanoma vaccine.
Another promising approach includes the use of interferon and/or
interleukin -2, biologicals which have shown reasonable success in
melanoma patients but unfortunately, interleukin-2 is particularly
toxic. This approach is not specific for melanoma but has been
also used in patients with renal cell cancer.
A third approach utilizes augmented "killer lymphocytes", which
patients with melanoma frequently develop. These "killer
lymphocytes" appear to seek and destroy melanoma cells.
Alteration of these naturally occurring killer cells using
recombinant DNA methods may actually increase their ability to
kill melanoma cells. This technique is quite new and will not be
available for many years.
Currently, while there are several promising treatments for
melanoma, prevention remains the most obvious way of combating the
disease. An understanding of the long term risks of excessive sun
exposure and taking steps to reduce that exposure is the single
most effective way of reducing the likelihood of disease.
Everyone should perform a regular self examination looking for
these danger signs in moles on your skin. Check carefully under
arms, between toes, back and top of your head, back... everywhere.
Become familiar with the moles you have, then watch for changes:
ASYMMETRY: One half the mole is unlike the other half.
BORDER IRREGULAR: The mole appears ragged or scalloped.
COLOR VARIED: The mole changes color from one area to another.
Shades of brown and tan may contain red, white, and blue.
DIAMETER: Moles larger than 1/4 inch (the width of a pencil
eraser.
Not all moles that fit into one of these categories is cancer, but
they should be brought to the attention of your physician.
Malignant melanoma often signals its presence by a change in an
ordinary mole. A mole that grows darker, wider, thicker, becomes
irregular, or starts to itch, hurt, or bleed should get immediate
attention. If a melanoma is found early and removed, the disease
can be completely cured. Do NOT put it off.
Support Group, Inc., has made arrangements with the Eastern
Cooperative Oncology Group (ECOG) to establish a research fund in
Howard's name. The money in this fund will be devoted to
supporting research aimed toward finding a cure for malignant
melanoma using biological agents. An initial donation of $5,000
has been made, and Support Group's share of TAPCIS Forum revenues
will be donated to this cause.
Anyone interested in making a donation in Howard's name is
encouraged to make a check out to ECOG and send it to Support
Group, Inc., P.O. Box 130, McHenry, MD 21541. We will be sending
details on each contributor to Howard's family, so feel free to
include a note if you wish.
If you would like more information about the ECOG, please feel
free to drop a mail or forum message to Richard Wilkes, President,
Support Group, Inc., 76701,23. Dr. John Wexler was a great source
of information for Howard during his illness, and John has also
offered to help answer questions you may have. John can be reached
at user ID 71360,3070.